Company Overview:
Asymchem is a leading global CDMO with over 25 years of experience supporting top pharmaceutical and biotech companies in advancing new therapies from early development through commercial production. With eight R&D and manufacturing sites, a team of 9,700+ professionals, and a strong regulatory track record, we bring deep technical expertise and unwavering commitment to quality.
Duties & Responsibilities:
- Be responsible for the route design and optimization of oligonucleotide synthesis processes, conduct small-scale and pilot-scale process studies, and promote the transition of processes to industrial-scale production.
- Lead the formulation and implementation of technical solutions for R&D projects, coordinate internal and external resources to ensure effective control of safety, quality, cost, and timelines.
- Establish and improve the technical documentation system related to process development, including process protocols, standard operating procedures (SOPs), and technical reports, to support process scale-up and regulatory submission.
- Monitor domestic and international advancements in oligonucleotide synthesis technology, and introduce new technologies and methodologies based on project needs to continuously improve process efficiency and product quality.
- Participate in cross-departmental collaboration, assist in resolving technical issues arising during production, and provide process training and technical guidance to relevant teams.
Job Requirements:
- Ph.D.'s degree or in Organic Synthesis or a related field; candidates with relevant work experience may be considered with relaxed educational requirements.
- Prior experience in process R&D/production in oligonucleotides or related fields is preferred; familiarity with GMP regulations is an advantage.
- Strong literature retrieval and information integration skills, with the ability to efficiently access and apply cutting-edge industry technical information.
- Solid data processing and analytical skills, with priority given to candidates capable of systematic summarization and analysis of experimental and production data.
- Excellent communication and coordination skills, with the ability to effectively drive cross-functional collaboration and project progress.
- Good command of English; preference will be given to candidates with proficient technical reading and communication abilities.